Eosinophilic oesophagitis as a cause of dysphagia and recurrent food impaction in a young male - long way to diagnosis. A case report
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چکیده
We describe the case of a 32-year-old male with recurrent dysphagia and food impaction caused by eosinophilic oesophagitis. Prior to establishing diagnosis, the patient underwent three oesophagogastroduodenoscopies (EGD) with repeated mucosal biopsies and several diagnoses, e.g. Mallory-Weiss syndrome, gastro-oesophageal reflux disease, were suspected. Despite several mucosal features highly suspicious of being eosinophilic oesophagitis, shown on second EGD, histopathology did not confirm the diagnosis. Histopathologic evaluation of biopsy specimens taken during the third EGD showed eosinophilic infiltration of oesophageal mucosa and confirmed the diagnosis of eosinophilic oesophagitis. The authors conclude that eosinophilic oesophagitis might be a common cause of dysphagia and food impaction in young adults, especially men with associated immunoallergic disorders. This clinical entity is probably underdiagnosed because of the lack of awareness of both endoscopists and pathologists. This might have been the cause of delay of diagnosis in our case, too.
منابع مشابه
Eosinophilic oesophagitis: an enigmatic, emerging disease.
Eosinophilic oesophagitis is a disease that has emerged in recent years. It is often associated with dysphagia and oesophageal food impaction in adults. The disease is characterised by infiltration of eosinophilic granulocytes into the oesophageal mucosa. This infiltrate may be responsible for the subtle peristaltic abnormalities that can be found in these patients. Endoscopic findings are usua...
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Eosinophilic oesophagitis is a chronic inflammatory disease characterized by eosinophilic infiltration of the oesophageal mucosa. Food and aero-allergens are involved in its pathogenesis. Dysphagia and food impaction are the dominant symptoms in adult with eosinophilic oesophagitis. However, a wide range of symptoms has been noticed such as chest pain or gastro-oesophageal reflux disease-like s...
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